Neonatal Isolation Enhances Anxiety-like Behavior Following Early-life Seizure in Rats
نویسندگان
چکیده
منابع مشابه
Enriched early life experiences reduce adult anxiety-like behavior in rats: a role for insulin-like growth factor 1.
Early life experiences can affect brain development, contributing to shape interindividual differences in stress vulnerability and anxiety-like behavior. In rodents, high levels of maternal care have long-lasting positive effects on the behavior of the offspring and stress response; post-weaning rearing in an enriched environment (EE) or massage counteract the negative effects of maternal separ...
متن کاملExercise during adolescence attenuated depressive-like behaviors and hippocampal mitochondrial dysfunction following early life stress in adult male rats
Purpose: In this study, we assumed that treating animals with an antidepressant agents or voluntary running wheel exercise (RW) during adolescence may have protective effects against early life stress (ELS) which can impact on behavior and mitochondrial function. Evidence indicates that ELS has deleterious effects on brain and behavior and increases the risk of mental disorders such as depressi...
متن کاملExercise during adolescence attenuated depressive-like behaviors and hippocampal mitochondrial dysfunction following early life stress in adult male rats
Purpose: In this study, we assumed that treating animals with an antidepressant agents or voluntary running wheel exercise (RW) during adolescence may have protective effects against early life stress (ELS) which can impact on behavior and mitochondrial function. Evidence indicates that ELS has deleterious effects on brain and behavior and increases the risk of mental disorders such as depressi...
متن کاملCorticotropin-releasing factor receptor antagonism within the dorsal raphe nucleus reduces social anxiety-like behavior after early-life social isolation.
Social isolation of rats during the early part of development increases social anxiety-like behavior in adulthood. Furthermore, early-life social isolation increases the levels of corticotropin-releasing factor (CRF) receptors in the serotonergic dorsal raphe nucleus (dRN) of adult rats. Interactions between serotonin and CRF systems are thought to mediate anxiety behavior. Therefore, we invest...
متن کاملEffect of chronic morphine exposure during the neonatal period on the anxiety like behavior of immature rats
Introduction: Several studies have reported anti-anxiety effects of morphine in adult rats. The present study examined the effect of chronic morphine injections in infancy and before puberty on anxiety-like behavior in immature rats. Methods: Neonate rats (n=35) were randomly chosen and divided into two groups. On postnatal days 8-14, one group received saline and the other one received mor...
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ژورنال
عنوان ژورنال: Pediatrics & Neonatology
سال: 2008
ISSN: 1875-9572
DOI: 10.1016/s1875-9572(08)60006-6